Soumis par assosefa le jeu 04/06/2020 - 09:50
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Résumé

This PhD project focuses on the mechanisms by which environmental pollutants and their mixtures cause adverse effects on early development and neurodevelopment. It will employ a combination of in vitro models (including stem-cell based) and zebrafish embryo assays. Molecular events (gene/protein expression) will be connected to in vivo effects via the Adverse Outcome Pathway framework to enable prediction of adverse effects from in vitro responses. The mechanism-based approaches will be linked to environmental risk assessment.
The ESR will be employed and enrolled in the doctoral programme of Environmental Health at Masaryk University, Czech Republic. International collaborations and secondments are foreseen namely with Vrije Universiteit Amsterdam (VUA), Netherlands and DuPont Nutrition& Biosciences, Denmark.
For further information about the scientific content please contact the principle supervisor: Assoc. Prof. Klara Hilscherova (klara.hilscherova@recetox.muni.cz).

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